Morphology & Grade
ICD-O-3 Morphology Codes
If the diagnostic term in the pathology report is not in the list below, be sure to consult your ICD-O manual.
- Adenocarcinomas (81403) of the kidney parenchyma are the most common (85% of all tumors).
- Hypernephroma, renal cell carcinoma or Grawitz tumor (83123)
- Clear cell (83103)
- Papillary (82603)
- Granular cell (83203)
- Spindle cell (80323)
- Transitional cell carcinoma (81203) most common morphology in renal pelvis; may be a function of a urothelial field defect.
- Papillary carcinoma (81303)
- Squamous cell carcinoma (80703) < 15% of renal pelvis tumors
- Other histologies
- Wilms tumor (nephroblastoma; 89603)—large bulky tumor of childhood; rare in adults
- Lymphoma (many cell types)
- Sarcoma (many cell types)
- Hemangiopericytoma (91503)
Grade of tumor correlates with stage; superficial tumors are usually grade I-II; infiltrating tumors are commonly grade III-IV.
Synonyms for in situ carcinoma: CIS, Stage 0, CIN grade III, confined to epithelium, intraepithelial, involvement up to but not including the basement membrane, noninfiltrating, noninvasive, no stromal involvement, papillary noninfiltrating, noninvasive papillary, stage "Ta"
Suggested Citation
SEER Training Modules: Morphology & Grade. U.S. National Institutes of Health, National Cancer Institute. Cited 01 January 2026. Available from: https://training.seer.cancer.gov.