Other Therapies

Radiation Therapy

Seminoma of the testis is highly curable with radiation therapy.

Radiation therapy can be administered to the abdominal and pelvic nodes, mediastinum and/or supraclavicular nodes prophylactically or in lieu of a lymph node dissection for lower-stage disease.

Key Words:

Hockey stick technique—radiation to the pelvic, periaortic, hilar and suprahilar lymph nodes. The fields form the shape of a hockey stick.

Systemic Therapy

Chemotherapy

Combinations of actinomycin, adriamycin, bleomycin, cisplatinum, cyclophosphamide, etoposide, vinblastine.

Examples:

  • PEB or BEP (platinum, bleomycin, VP-16)
  • CVB (platinum, velban, bleomycin)
  • PVB (cisplatin, vinblastine, bleomycin)
  • VAB-6 or VAB VI (vinblastine, dactinomycin, bleomycin, cytoxan, cisplatin)
  • EP (etoposide, cisplatin)
  • VPV (vinblastine, cisplatin and etoposide)
  • POMB/ACE (cisplatin, vincristine, methotrexate, bleomycin, dactinomycin, cytoxan, etoposide)
  • Carboplatin, etoposide, bleomycin (under clinical evaluation)

Hormones (not shown to be useful in testicular cancer)

Biological Response Modifiers (under clinical evaluation)