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Head & Neck Staging: Table Two
| TNM Classification | Histological/Clinical Features |
|---|---|
| TX | Primary tumor cannot be assessed |
| T0 | No evidence of primary tumor |
| Tis | Carcinoma in situ |
| TNM Classification | Histological/Clinical Features |
|---|---|
| T1 | 2 cm or less |
| T2 | > 2 but < 4 cm |
| T3 | > 4 cm |
| T4 | Invades adjacent structures |
| T4a | Invades larynx, deep/extrinsic muscle of tongue, medial pterygoid, hard palate, or mandible |
| T4b | Invades lateral pterygoid muscle, pterygoid plates, lateral nasopharynx, or skull base or encases carotid artery |
| TNM Classification | Histological/Clinical Features |
|---|---|
| T1 | Limited to one sub site of hypopharynx and 2cm or < |
| T2 | > 2 but < 4 cm without fixation or more than one sub site or adjacent site |
| T3 | > 4 cm or with hemilarynx fixation |
| T4a | Invades thyroid/cricoid cartilage, hyoid bone, thyroid gland, esophagus, or central compartment soft tissue |
| T4b | Invades prevertebral fascia, encases carotid artery, or involves mediastinal structures |
| TNM Classification | Histological/Clinical Features |
|---|---|
| T1 | Confined to nasopharynx |
| T2 | Extends to soft tissue of oropharynx and/or nasal fossa |
| T2a | Without parapharyngeal extension |
| T2b | With parapharyngeal extension |
| T3 | Invades bony structures and/or paranasal sinuses |
| T4 | Intracranial extension, and/or involvement of cranial nerves, infratemporal fossa, hypopharynx, or orbit |