Morphology & Grade

ICD-O Morphology Codes

If the diagnostic term in the pathology report is not in the list below, be sure to consult your ICD-O manual.

Pancreas

• Adenocarcinoma (81403)
  • Mucinous (colloid) carcinoma (84803)

• Duct cell carcinoma (85003; 90% of all cases)
• Islet cell carcinoma (81503; NOS arise in Islets of Langerhans)

• Insulinoma (81513; produce insulin)
• Glucagonoma (81523; produce glucagon)
• Gastrinoma (81533; produce gastrin)

Other histologies

• Wilms tumor (nephroblastoma; 89603)—large bulky tumor of childhood; rare in adults
• Lymphoma (many cell types)
• Sarcoma (many cell types)
• Hemangiopericytoma (91503)

• Cystadenocarcinoma (84403; arise in tail of pancreas)
• Other cell types: papillary cystic carcinoma (84521); adenoacanthoma (85703);
• pancreatoblastoma (89713) and many others
• Mixed islet cell and exocrine adenocarcinoma (81543)
• Lymphomas and sarcomas (many cell types)

Key words

• Apudoma (82481)
• Vipoma tumor producing vasointestinal peptide

Gallbladder

• Adenocarcinoma (81403)
  • Subtypes: signet ring cell, clear cell, colloid, oat cell and others

Liver

• Hepatoma (81703; 70-90 % of all primary liver tumors; also called hepatocellular, hepatocarcinoma, or liver cell carcinoma)
• Fibrolamellar hepatocellular carcinoma (81713)
• Combined hepatocellular carcinoma and cholangiocarcinoma (81803)

Ampulla of Vater

• Adenocarcinoma (81403)

Bile Ducts (intra and extrahepatic)

• Cholangiocarcinoma (81603; also called bile duct carcinoma) Klatskin's tumor (81623) Adenocarcinoma (81403; most common for extrahepatic bile duct tumors) Sarcomas (several types)

Synonyms for in situ carcinoma: (adeno)carcinoma in an adenomatous polyp with no invasion of stalk, confined to epithelium, noninfiltrating, intraepithelial, involvement up to but not including the basement membrane, noninvasive, no stromal involvement, papillary noninfiltrating.