- Men develop NHL 30 percent more often than women.
Eighty-five percent of childhood Hodgkin lymphoma cases
are in males, as are all lymphoma histologies in adults
except nodular sclerosing.
- HL (Hodgkin Lymphoma) peaks in the 20-29 age range
and again in the 50+ range. The histologies for these
two peaks are different.
- Caucasian children are at slightly greater risk than
African-American children.
Others at risk are:
- People with inherited immune deficiency diseases,
such as chronic immunosuppression (for
organ transplants), acquired immunosuppression, Klinefelter
syndrome, Chediak-Higashi
syndrome, lymphocytopenia,
lymphoid infiltrates in the skin; malignant lymphoma,
mycosis fungoides, Sezary's disease, malignant histiocytosis,
Letter-Siwe's disease, multiple myeloma, plasmacytoma,
any leukemia, Waldenstrom's macroglobulinemia.
- People with autoimmune disease, such as rheumatoid
arthritis or systemic lupus erythematosus.
- People infected with HIV (particularly primary lymphoma
of the brain).
- People taking immunosuppressant drugs following organ
transplant.
- People who have received radiation therapy and/or
chemotherapy.
- People who work extensively with or are otherwise
exposed to chemicals, such as pesticides or some fertilizers.
- People who have persistent generalized lymphadenopathy,
lymphatic disorders, including frequent lymphoid hyperplasia,
chronic lymphadenopathy, infectious mononucleosis,
exposure to Epstein-Barr virus.
