| Spread | Primary Site/Mets |
| Lymphatic Spread | Rare; leukemia is considered systemic at the time of diagnosis. |
| Hematogenous Spread | Leukemia may invade many visceral sites, including skin, breast, eye, spleen, lymph nodes |
Key words/involvement: terms which indicate possible involvement by tumor. Common terms are provided, but the list is not all-inclusive.
Other words/no involvement: other terms seen in reports
which indicate an abnormality but do not indicate
a neoplastic process. Common terms are provided, but the list is not all-inclusive.
Key information: information to look for in the report
of the study. Key information helps define the
extent of disease.