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9989/3 Myelodysplastic Syndromes (MDS)
Definition disruption of production of blood cells--white, red, platelets; development of poor quality blood cells resulting in low levels of mature, functional cells; < 30% blasts in marrow
ICD-9 code 238.7 unless indicated otherwise below
Synonyms Pre-leukemia; preleukemic disorders
Smoldering leukemia; oligoblastic leukemia; subacute myeloid leukemia
de novo myelodysplastic syndrome - develops with no known cause
Secondary myelodysplastic syndrome - develops following chemotherapy or radiation therapy for another disease; has poorer prognosis than de novo MDS
Dysmyelopoietic syndrome; hemopoietic dysplasia