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Systemic Therapy

Under clinical investigation for treatment of various head and neck cancers is Isoretinoin (Retin-A). Used daily for a year, it may prevent development of subsequent primaries.

Key words

Neoadjuvant chemotherapy--chemotherapy administered prior to surgery or radiation therapy, intended to shrink tumor mass and make it more treatable by another modality.

Chemotherapy agents used alone or in combinations:

Cisplatin
5-FU
Bleomycin
Methotrexate
Doxorubicin (adriamycin)
Cyclophosphamide

Biological Response Modifiers

Interferon

 

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