| TNM Classification |
Histological/Clinical Features |
| Larynx (C32.0, C32.1,
C32.2, C10.1) |
| TX |
Primary tumor cannot be assessed |
| T0 |
No evidence of primary tumor |
| Tis |
carcinoma in situ |
| Supraglottis |
|
| T1 |
Limited to one subsite, with normal vocal cord mobility |
| T2 |
Invades mucosa of > one adjacent subsite of supraglottis or glottis
or region outside the supraglottis; without fixation of larynx |
| T3 |
Limited to larynx with vocal cord fixation and/or or invades postcricoid
area, pre-epiglottic tissues, paraglottic space, and/or minor thyroid
cartilage erosion. |
| T4a |
invades through thyroid cartilage and/or tissues beyond larynx |
| T4b |
invades prevertebral space, encases carotid artery, or invades mediastinal
structures |
| Glottis |
|
| T1 |
Limited to vocal cord(s), with normal mobility |
| T1a |
limited to one vocal cord |
| T1b |
involves both vocal cords |
| T2 |
Extends to supraglottis, and/or subglottis, and/or with impaired cord
mobility |
| T3 |
Limited to larynx with vocal cord fixationT4 = Invades thru thyroid
cartilage and/or other tissues beyond larynx |
| T4a |
invades through thyroid cartilage and/or tissues beyond larynx |
| T4b |
invades prevertebral space, encases carotid artery, or invades mediastinal
structures |
| Subglottis |
|
| T1 |
Limited to subglottis |
| T2 |
Extends to vocal cord(s) with normal/impaired mobility |
| T3 |
Limited to larynx with vocal cord fixation |
| T4a |
invades cricoid or thyroid cartilage and/or tissues beyond larynx |
| T4b |
invades prevertebral space, encases carotid artery, or invades mediastinal
structures |
