Criteria for TNM Clinical Staging: Physical examination; palpation of breast, axillary, supraclavicular and cervical nodes; pathologic examination of breast or other tissue to establish a diagnosis of cancer, including size of tumor, chest wall invasion, and presence or absence of positive nodes and distant metastases.
Criteria for TNM Pathologic Staging: Removal of all primary tumor (no tumor at any margin of resection on gross examination) and at least Level I nodes (lateral to lateral border of pectoralis minor--at least 6 nodes in this area).
| Tis | In situ |
| T1 | 2cm |
| T1mic | 0.1 cm |
| T1a | > 0.1 to 0.5 cm |
| T1b | > 0.5 to 1 cm |
| T1c | >1 to 5 cm |
| T2 | >2 to 5 cm |
| T3 | > 5 cm |
| T4 | Chest wall/skin |
| T4a | Chest wall |
| T4b | Skin edema/ulceration, satellite skin nodules |
| T4c | Both 4a and 4b |
| T4d | Inflammatory carcinoma |
| N1 | Movable axillary pN1 |
| N2 | Fixed axillary |
| N3 | Internal mammary |
| pN1a | Micrometastases only, # 0.2 cm |
| pN1b | Gross metastases i 1-3 nodes, >0.2 to < 2 cm ii 4 nodes/>0.2 to < 2 cm iii through capsule/ < 2 cm iv 2 cm |
Fore more details on Collaborative Stage, see the CS module.