| Abbreviation | Term(s) |
| Each eye (oculus uterque) | OU |
| Ears, nose & throat | ENT |
| Electrocardiogram | ECG, EKG |
| Electroencephalogram | EEG |
| Electromyogram | EMG |
| Electroshock therapy | EST |
| Emergency room | ER |
| Endoscopic retrograde cholangiopancreatography | ERCP |
| Enlarged | ENL |
| Erect (standing), posterior, anterior | EPA |
| Esophagogastroduodenoscopy | EGD |
| Estrogen receptor (assay) | ER(A) |
| Examination | EXAM |
| Examination under anesthesia | EUA |
| Excision | EXC |
| Exploratory laparotomy | EXP LAP |
| Extend, extension | EXT |
| Extended care facility | ECF |
| External | EXT |
| Extremity | EXT |
| Eyes, ears, nose & throat | EENT |