| Abbreviation | Term(s) |
| Date of birth | DOB |
| Date of death | DOD |
| Dead on arrival | DOA |
| Deep tendon reflex | DTR |
| Deoxyribonucleic acid | DNA |
| Dermatology | DERM |
| Diagnosis | DX |
| Diameter | DIAM |
| Differentiated, differential | DIFF |
| Dilatation and curettage | D&C |
| Discharge | DIS, DISCH |
| Discharge | DC, DS |
| Discharge diagnosis | DD |
| Discontinued | DC |
| Disease | DIS |
| Doctor of Osteopathy | DO |
| Dyspnea on exertion | DOE |